Oocyte donation for assisted fertilisation in Italy

ProCrea, Fertility and Fertilisation Center

Tel. +39 02 600 630 41

Oocyte Donation: Therapeutic process
ProCrea offers to its patients a 360 degree support for the diagnostic and therapeutic process in the cases where oocyte donation is indicated.

The process is based on a network of excellent international partnerships within the reproductive medicine sector that ProCrea has selected and validated, both for the selection of the oocyte donor and for the laboratory techniques necessary for this type of therapy. Thanks to the collaboration that started with Le Betulle of Appiano Gentile (COMO - Italy) and its proximity to our Lugano facility, we can provide couples at every step of the process.

For the protection of the people involved, the law requires mutual confidentiality and anonymity .

Oocyte donation access and procedures
The requirements to qualify for oocyte donation are the following:
- no ovarian functionality;
- early physiological menopause;
- surgical menopause (partial or complete ovary removal);
- genetic diseases that can be transmitted to the child;
- multiple fertilisation failures using assisted procreation techniques;
- multiple embryo implantation failures;
- endometriosis.

Oocyte donation includes the three following steps:

1. Activation of the receiving woman's reproductive system so that the endometrium is ready to receive the embryos;

2. The donated oocytes are fertilised through FIVET (bringing the ova into contact with the partner's or, in some cases, the donor's sperm) or ICSI (each ovum is injected with a specifically selected sperm);

3. Transfer of the embryos into the recipient's uterus with an out-patient procedure which does not require anaesthesia or hospitalisation. The number of embryos to be transferred is determined by the doctors.

ProCrea, a combination of science and expertise
The oocyte donors undergo specific tests in order to ensure that they are not affected by genetic, hereditary or infective diseases that could be transmitted to the child. The information collected includes phenotypical and psychological characteristics of the donors so that, when selecting the oocyte, the medical team can ensure the maximum phenotypical similarities with the receiving woman.

The results of an oocyte donation have a very high statistical success rate: where it is possible to use young oocytes in perfect health, the success rate averages approximately 60 % at the first attempt.

The Procrea staff are available for any additional information about oocyte donation.

The ProCrea Oocyte Donation Team

The Oocyte Donation Team is composed of physicians and biologists, specialised in the physiopathology of reproduction, offering the highest level of skills and knowledge.

Furthermore, a team of assistants and nurses, working with the physicians, guarantees 24/7 assistance to the couples and facilitates their positive participation in the diagnostic and therapeutic procedure of oocyte donation.

Iride Zanotti is the oocyte patient coordinator of ProCrea and manager of the ProCrea Oocyte Donation Team. She will be at your side throughout the entire process both at ProCrea and at Le Betulle Center. Iride is fully available to you for:

1. Administrative assistance for the patient undergoing oocyte donation therapy;
2. Search for a donor;
3. Coordination with the medical team in order to provide a constant update on the progress of the donor's stimulation, the positive outcome of the pick up from the donor and the date of delivery of the batch to Le Betulle;
4. Assistance and support provided at Le Betulle Center.

ProCrea Oocyte Donation Team
email: ovodonazione@procrea.ch
Tel.: +39 02 600 630 41

OOCYTE DONATION THERAPY COST (first cycle): Euro 8'500.- (6 oocyte) - Euro 9'500.- (8 oocyte)
What is included:

1. Medical exams, ultrasound and hormonal collection during the endometrial preparation of the recipient (if carried out at ProCrea)
2. Thawing of the oocyte (one oocyte batch comprises 6 or 8 oocytes) and fertilisation
3. Transfer of 1 or 2 embryos (decision to be made in conjunction with the doctor)
4. Blood collection and determination of the BetaHCG level (hormone that indicates pregnancy) if carried out at ProCrea
5. Screening, medications and oocyte collection from the donor
6. Preparation and transport of the semen, if necessary

What is not included:

- Woman: trial transfer + hydrosone , diagnostic tests and medications
- Man: seminogram and cryopreservation of the semen, diagnostic exams

Male heterologous insemination, if necessary, Euro 500 .-

Any thawing and transfer, after the first one, for cryopreserved embryos, Euro 2,000 - each attempt.

Cost for any second complete cycle with a new donor : Euro 7,000 -

The ProCrea staff are available for additional information about the oocyte donation procedure.


"Many thanks to ProCrea and to the staff of Dr Bellavia. You will always be in my heart."

I have been treated at ProCrea. Mine was not an easy procedure because I have a few problems, but thanks to constant consultations with the doctor and her recommendations, I had the courage to continue. I was lucky, everything went well and I am now the mother of a beautiful baby boy. I was treated by Dr Bellavia, whom I had met last year during an outreach day that ProCrea organises monthly, I believe, and I decided to set up an appointment. On that day, when I met with her after the presentation, she talked to me about endometriosis, which was my problem. The path of those who choose assisted fertilisation is very often not an easy one. I have experienced it myself, but I can guarantee you that ProCrea is the right Center, where you are going to be treated and given answers to all your questions and concerns. Again, many thanks to ProCrea and to the team of Dr Bellavia. You will always be in my heart.

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“Based on my experience, I can only say thanks to Dr Bellavia”.

I had a couple of failures at an Italian Center, therefore I understand the feelings of those who did not have a good experience, especially when you have a doctor who, after you completed the process (for which you paid), gets rid of you quickly by saying “It's your fault for waiting”. My husband and I did not give up and following the advice of friends with similar problems, we came to ProCrea. We made sacrifices to pay the extra, but finally we succeeded, although not on our first attempt. Based on my experience, I can only say thank you to Dr Bellavia. In Italy, I was not as closely followed as I have been at ProCrea. Good luck and do not ever give up!

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"After many negative outcomes, I decided to try with ProCrea"

Hello, I would like to tell you about my experience at ProCrea with the hope it will be encouraging to you. After being treated in Italy at two different Centers and after several negative outcomes, I decided to go to ProCrea. I did the oocyte donation with Dr Bellavia and finally we obtained the outcome we had been anxiously waiting for. Any time I had some concerns (which happened often), I called the doctor and she was always very kind and always fully answered my questions. I encourage you not to give up because if I had, I would not be pregnant now. Good luck.

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"At the first attempt at the Center, I became pregnant with twins"

After 10 years of unsuccessful treatments between Icsi and Fivet, at two prestigious hospitals in Northern Italy, and after so much pain and frustration, I went to the ProCrea Center, as my last attempt, this time to try a different therapy: oocyte donation. I am not young, I am 45 years old, but at the first attempt at the Center I became pregnant with twins, now I am in the third month of pregnancy and the babies are growing well, thank God. I am so thankful to Dr Bellavia, her team and all the professionals at the ProCrea Center for giving me the support that I needed every time but mostly for helping my husband and me to finally achieve this wonderful dream!

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Assisted fertilisation, the first babies born from oocyte donation with ProCrea
Two Italian twins made a young couple's dream of being parents come true. «Oocyte donation helps women to overcome even severe infertility problems», explains the ProCrea Medical reproduction Center in Lugano.

The first children from oocyte donation have been born thanks to the ProCrea Medical Reproduction Center. These are two beautiful twins, a girl and a boy, of Italian nationality. The parents, who had been wanting a pregnancy for a long time and had many failed attempts, approached ProCrea. «They came here in the summer of 2014», recalls Michael Jemec, Medical Director of ProCrea in Lugano. «Even though the woman was in a quite difficult situation, and considering her not particularly advanced age, we proceeded with a first treatment with the Fivet technique. Unfortunately this approach was unsuccessful. Repeating the same procedure would not have resulted in a positive outcome, so in March 2015 we proposed to do the oocyte donation. They accepted and we started the procedure».

The search for a donor, based on specific traits of the future mother, generated good results in a short period of time. Therefore, within a few months, it was possible to initiate the entire process: from the stimulation with the collection of the ova from the donor up to the activation of their fertilisation with the sperm of the woman's partner and the implantation of the embryo. «It all worked out well. And at the beginning of April, the woman delivered beautiful twins. The boy weighed 2.5 kg, the girl a little less,2.45. They are both in good health, as is their mother, continued Jemec. «An incredible joy for the couple, but also for us. The commitment of our staff, thanks to international partnership with selected facilities, has led to the realisation of their dream. For ProCrea, these twins are the first babies born with oocyte donation, a technique that can solve even serious female infertility problems».

For one woman out of ten, with infertility problems, oocyte donation is the only path to pregnancy and motherhood. «It is not an insignificant procedure», adds the ProCrea specialist «Having children, for some women, is a very natural path while others have to overcome many obstacles. Oocyte donation is the path that in some situations allows couples to realise a dream. The dream of a lifetime». Oocyte donation is a heterologous-type assisted fertilisation technique involving the donation of oocytes from one woman to another in order to overcome infertility situations.

«It is a programme that starts only after many in depth exams and after diagnosing problems that are not solvable in any other way», explains Jemec.

«Oocyte donation is applicable for situations of no ovarian functionality, advanced endometriosis and early physiological or surgical menopause. In this case, we are facing a situation that involves a repeated number of failures using assisted procreation techniques: a situation of infertility of a couple that did not show any apparent cause: the age was not particularly advanced, the male parameters were strong, but the female showed difficulties in fertilising the oocyte. Resorting to a donor allowed the couple to realise their dream».

Via Clemente Maraini 8
CH 6900 Lugano
T.: +41 91 924 55 55
F.: +41 91 924 55 56

Call from Italy with no additional costs:
+39 02 600 630 41

A team composed of more than 50 professionals including physicians, biologists, geneticists, nurses and auxiliary personnel is the guarantee for an efficient and safe structure.


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